Abel Lab Current Projects
A virtual assessment kit is mailed to participating patients
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Patient-Centered Care for Older Adults with Hematologic Malignancies
The Older Adult Hematologic Malignancy (OHM) Program is a specialized clinical and research initiative that measures the functional status of older adults with blood cancers, characterize the prognostic value of the geriatric domains measured, and develop interventions to improve function. This program seeks to better understand the impact of frailty on outcomes such as survival and healthcare utilization, and provide embedded geriatric management when appropriate to optimize care for this patient population. Read more about the OHM Program here. |
Shared Care: Patient-Centered Management after Hematopoietic Cell Transplantation
This study assesses the effectiveness of a shared approach to care after hematopoietic cell transplantation, in which patients receive part of their care with their local oncologist and part of their care at Dana-Farber. This is compared to “usual care” occurring exclusively at Dana-Farber in Boston. Effectiveness is assessed with respect to relevant patient-reported outcomes and traditional HCT outcomes.
This study assesses the effectiveness of a shared approach to care after hematopoietic cell transplantation, in which patients receive part of their care with their local oncologist and part of their care at Dana-Farber. This is compared to “usual care” occurring exclusively at Dana-Farber in Boston. Effectiveness is assessed with respect to relevant patient-reported outcomes and traditional HCT outcomes.
Understanding and Improving End Of Life Care for Patients with Blood Cancers
The Abel lab works closely with the Odejide lab to improve end of life (EOL) care for patients with blood cancers. Projects have addressed the best way to measure the quality of EOL care received by this patient population, changes in EOL care practices over time, and eliminating barriers to hospice use. The two labs are also interested understanding how insurance type may be associated with the quality of care received by patients with blood cancers at the EOL.
The Abel lab works closely with the Odejide lab to improve end of life (EOL) care for patients with blood cancers. Projects have addressed the best way to measure the quality of EOL care received by this patient population, changes in EOL care practices over time, and eliminating barriers to hospice use. The two labs are also interested understanding how insurance type may be associated with the quality of care received by patients with blood cancers at the EOL.
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The Dana-Farber Cancer Ethics Research Initiative (CERI)
Working closely with the Dana-Farber Ethics Advisory Committee (which Dr. Abel co-chairs), the Cancer Ethics Research Initiative aims to address ethical implications of cancer care and research. The program focuses on topics such as the ethics of sharing clinic notes with patients, ethical approaches to address chemotherapy shortages, optimizing clinical ethics consultations, and ethical implications of artificial intelligence (AI) models for decision-making in oncology research and care delivery. |
Members of the Ethics Advisory Committee meet regularly to discuss clinical and institutional ethics
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Understanding and Optimizing Clinical Trial Enrollment for Patients with Acute Leukemia
The past decade has seen an explosion in new treatments for acute leukemia, all of which were tested through rigorous clinical trials. The Abel Lab aims to find interventions to ensure that all patients have access to leukemia trials and eventually, the treatments that are developed.
The past decade has seen an explosion in new treatments for acute leukemia, all of which were tested through rigorous clinical trials. The Abel Lab aims to find interventions to ensure that all patients have access to leukemia trials and eventually, the treatments that are developed.
Our gait application was developed by Dr. Brad Manor and team at Hebrew SeniorLife and is supported by OneStep
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Technology to Assess In-Home Function in Older Adults with Blood Cancers This study investigates the feasibility of longitudinal, in-home measurement of function and gait speed in older adults with blood cancers through the use of in-home measurement technologies. Technologies being investigated include smartphone-based accelerometers and passive activity monitors, with the goal of direct input into the electronic health record. |
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Testing an Avatar-based Intervention to Support Patients Undergoing Stem Cell Transplantation
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Charlie, the AI-powered care.coach avatar, works with patients as they go through stem cell transplant
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Optimizing Exercise for Older Adults with Myeloid Malignancies and Clonal Hematopoiesis
Working with the Dieli-Conwright Lab, the Abel Lab is developing a protocol to develop and test an optimal exercise regimen for patients with myeloid malignancies and precursor conditions.
Working with the Dieli-Conwright Lab, the Abel Lab is developing a protocol to develop and test an optimal exercise regimen for patients with myeloid malignancies and precursor conditions.
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